Isolated Myrcene Terpene
- *Food-grade, natural, organic and non-GMO
- *Add to concentrates, edibles, topicals, etc.
- *Product development and formulations
- *Strain terpene profiles or proprietary blends
- *Maximize the “entourage effect”
- *Add to Tinctures of any brand
Myrcene is an earthy, citrusy terpene with an aroma suggestive of hops, cloves, and tropical fruits. Nuances of mint and mango are often detected in Myrcene’s strong fragrance. Strains known for their content of Myrcene include Phantom OG, Afghani, Bubble Gum, White Widow, Skunk #1, El Nino, Himalyan Gold, and Pure Kush. Isolated Myrcene can be naturally sourced from hops (Humulus lupulus), thyme (Thymus vulgaris), lemongrass (Cymbopogon citratus), mangoes (Mangifera indica), basil (Ocimum basilicum), and bay laurel leaves (Laurus nobilis). Myrcene is the most prevalent terpene naturally found in most varieties of cannabis. The cannabinoid THC works synergistically with Myrcene to create a stronger experience. Myrcene impacts the permeability of cells in the brain, increasing the absorption of THC (and other terpenes). Myrcene can be used to promote sedation, muscle relaxation, restful sleeping. Myrcene displays powerful pain-relieving properties, along with anti-inflammatory and antibacterial benefits. This has lead to the suggestion that Myrcene may have the potential to act as an alternate to some aspirin-like pharmaceuticals.
Myrcene Safety Data Sheet
Myrcia, Bay Tree, Mango, Ylang-ylang, Wild Thyme, Parsley, Hops, Houttuynia, Verbena
Balsam, Peppery, Spicy
Balsamic, Fruit, Geranium, Herb, Must
Analgesic, Antioxidant, Sedative
Oral administration of myrcene in rats was concluded to produce a dose-dependent pain relief for the hyperalgesia induced by subplantar injections of either carrageenin or prostaglandin E2, but did not affect that induced by dibutyryl cyclic AMP. These results indicated a peripheral site of action. In contrast to the central analgesic effect of morphine, myrcene did not cause tolerance on repeated dosing in rats. Myrcene shows promise as a lead for the development of new peripheral pain killers with a different method of action than aspirin-like drugs.
Myrcene was explored as a sedative in the mouse model. Muscle relaxation was seen as observed through the rota rod test. In addition there was an increase in sleeping time by 2.6x.
Myrcene was eluted to block the metabolic activation of some promutagens (e.g., cyclophosphamide and aflatoxin B1) in in vitro genotoxicity assays. The effects of myrcene was evaluated through the activity of liver microsomes. A concentration-dependent competitive inhibition was observed for pentoxyresorufin -O-depenthylase activity, a selective marker for a cytochrome p450. The potent inhibitory effects on the cytochrome p450 suggest that myrcene, could also interfere with the metabolism of xenobiotics, which are substrates for this isoenzyme
Synergistic effects with…
Analgesic – CBD, THC
Sedative – THC, CBN
Anti-oxidant – CBD, CBG
Sedative – nerolidol